@BraswellJay said in FreePBX : Skyetel inbound call "Rejecting unknown SIP connection ...":
Go into your @Skyetel endpoint setting and make sure it is talking to your PBX on port 5160 also.
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This seems likely to be my issue then. I had left it at 5060 in the skyetel portal as you showed above and initially had it port forwarded to 5060 on the FreePBX. When I realized that I had set port 5060 up as the chan_sip port instead of the pjsip I changed the firewall to forward 5060 to 5160 on the FreePBX. I'll try making the change in the Skyetel portal directly to 5160 and just direct port forward 5160 in the morning.
As @JaredBusch figured, this fixed my issue. Once I made this change I had two way audio and no call's being taken down prematurely.
Audio issues are always port related. Though mostly because firewalls are fucking things up.