I spend about 5 minutes a week adding a few domains to a blacklist. Not a big deal. My spam service is just fine, I'm talking about a few emails a week getting through. I would like to get it to 0 though I doubt that is possible. Gmail seems to be the best at spam blockage, wonder what they are doing.
This email address has existed since the mid 90's(company around since 1984) honestly every single spammer in the world probably has it. [email protected]. The fact that less than 10 spam messages/week get through mean the filters work well I think.
The big spam shops(NYC mostly as SAM says, if you believe their addresses in the sig) do send out emails with slightly different email address domains, all the time.
Had one that was always getting through, baddomain.com, I blacklisted it, two weeks later it was bad-domain.com