Windows 10 1709 file permissions issue
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Some of you might have seen my post this morning about PDFs not opening in IE.
After showing another error from these machines - JB told me that he's seen several situations where 1709 is having permissions issues.
So this could be a 1709 issue specifically not giving permissions.
Additionally I found that Webroot has a known issue (also around permissions) on 1709.
https://community.webroot.com/t5/Product-Questions/Windows-10-1709-Issues/td-p/305213 -
Well disabling the realtime scan on Webroot has solved my issue.
/shrug.